Dobe Owners: Lingenous Conjunctivitis

Discussion in 'Health and Nutrition' started by Rach, Nov 30, 2012.

  1. Rach
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    Rach Pup

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    Didn't know if any of you Dobe owners have heard of this. Godric is our first Dobe who we bought from a reputable breeder.
    Towards the later part of July his third eyelids were swelling and he was producing a lot of mucous. We thought he was having an issue with environmental allergies. He was getting puss filled bumps all over his body as well, rash like. We had him at the Vets it seemed like every day. He was on all sorts of eye drops, medicated shampoos, antibiotics etc. Everything we had him on would work well for about a week and then his eyes would start to get worse. By the time the mucous started to attach itself to his third eyelids our Vet recommended us to see a specialist at KState Veterinary Hospital. We made an appointment and drove the 4 hours to see an Ophthalmologist. He was greeted not by one but by 4 Dr's. They were able to preform a biopsy that day. The were suspecting that he had this rare, what they think is genetic, disease. They themselves have never seen it. I guess there has only been a case study of 4 worldwide. Anyways we got the results back and it was confirmed, Lingenous Conjunctivitis. It manifests in the eyes hence the name but what it does if untreated is forms plaque like deposits on various organs and will subsequently kill them. So this poor guy has been on Azathioprine (chemo like pills), Prednisone, a compounded eye drop and and pred acetate eye drop. We also have to regular blood work up to make sure his kidney enzyme levels don't get too elevated. KState will be publishing a paper on him, since this is their first case and because it's so rare. I guess they are just guessing at what the treatment needs to be since all of the other dogs who have had this have since perished. I won't bore you with an even longer novel. Just wondering if you all have heard of this.
     
  2. obbanner
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    obbanner Big Dog

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    No, I haven't heard of this. Thanks for posting - hope I never need this information! ;) Is Godric stabilized or is he getting worse?
     
  3. Rach
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    Rach Pup

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    He's doing better. His liver enzymes have been elevated but not enough to stop his medication. I think I put Kidney in the post above, it's the liver enzymes we have to watch. The first two pictures were taken at the beginning of treatment Oct 27. The last picture was taken on Nov 5. He goes back to K State this Sunday for a check up. I will get some new photos this weekend. They look so much better now.
    PIC_2222.JPG PIC_2223.JPG PIC_2228.JPG
     
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  4. obbanner
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    obbanner Big Dog

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    The poor guy! I'm glad to hear he's improving. Give him a hug for all of us here! Hope all goes well on Sunday. :fingersx:
     
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  5. Michele
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    Michele Canine Chat Owner Staff Member

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    I'm glad he is improving. Give him hugs from me please!! Keep us updated.
     
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  6. Rach
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    Rach Pup

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    I got some pics of his eyes this morning. I think they look so much better.
    PIC_2325.JPG PIC_2323.JPG
     
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  7. Deputy Dog
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    Deputy Dog Canine Chat Owner Staff Member

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    He does look so much better!

    Having said that, I'm sorry that his condition is due to a genetic mutation. I'm sure you know that's not a good thing. What is his prognosis?

    P.S. I fixed the code in your signature URL!

    2012-12-01_152946.png
     
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  8. Rach
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    Rach Pup

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    Thanks for fixing! Untreated his prognosis isn't good. With that said, I don't think they know enough about this disease so unfortunately I think Godric is going to be the gateway for this disease. I think we are winging treatment and cross fingers that it takes and goes well!
     
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  9. Rach
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    Rach Pup

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    Godric was back at the vets on Monday. When I got home Saturday from shopping he was holding his left eye closed. Turns out he has an ulcer on his cornea again. Not sure if this is something that we will fight with this disease or not. Allen was playing with him Monday night and noticed a hemotoma between his toes on his right front paw. Last week when we were out running him, Allen pulled a splinter out of his pad that was about 3" long. We put hydrogen peroxide and neosporin on it that night and didn't think much else of it, especially since he wasn't limping. Anyway, back to the vets we went today. They probed the area and pulled out a blade of grass around 1.5" long. He's on antibiotics for a week. Not to mention, that it's a good thing that he is done with the prednisone today. He weighs 101lb. A good weight for him is around 87lb. We've been rationing his food but it hasn't helped with him still on the steriod.
     
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  10. Deputy Dog
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    Deputy Dog Canine Chat Owner Staff Member

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    Tough break. Some days it don't pay to get out of bed. I bet Godric wishes he could have a mulligan! Hope he's well soon.
     
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  11. Rach
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    Rach Pup

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    Godric had a check up at KState today.... Great news.... he can now stop two of his three eyedrops... he will just have to have the Tacrolimus drops twice daily and his Azothioprine pill once a week!!!! We are doing the happy dance around here :yatta::yatta: He has also dropped some needed weight since he had been on the Prednisone for so long... we went from 103 to 98 today :D... about 10 more pounds and I think he'll look smashing :D
     
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  12. obbanner
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    obbanner Big Dog

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    Fantastic!!
     
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